Opioid withdrawal occurs when a person who has developed physical dependence on opioids suddenly stops or significantly reduces their use.
Medically Reviewed by Dr. Bryon McQuirt
May 16, 2025
While opioid withdrawal is rarely life-threatening, it can be extremely uncomfortable and challenging to endure without proper support. Understanding the symptoms, timeline, and treatment options for opioid withdrawal is essential for anyone seeking recovery from opioid dependence or supporting a loved one through this process.
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Physical dependence on opioids develops because these substances bind to opioid receptors in the brain, spinal cord, and other organs. With continued use, the body adapts to the presence of opioids and requires them to maintain normal functioning. When opioid use is reduced or stopped, the body must readjust to functioning without these substances, resulting in withdrawal symptoms.
Opioid withdrawal symptoms can range from mild to severe, depending on factors such as the type of opioid used, duration of use, dosage, individual physiology, and whether the person attempts to quit “cold turkey” or gradually tapers their dosage.
Psychological symptoms often accompany the physical symptoms and may persist longer. These can include:
While opioid withdrawal symptoms can be extremely uncomfortable, it’s important to note that unlike withdrawal from alcohol or benzodiazepines, opioid withdrawal is generally not life-threatening.
However, complications such as dehydration from vomiting and diarrhea can become serious if not properly managed, and the distress of withdrawal can increase the risk of self-harm or suicide in vulnerable individuals.
The duration of withdrawal varies significantly depending on the specific opioid used. Here’s a breakdown of common opioids and their typical withdrawal timeframes:
Heroin
Prescription Pain Medications (Short-Acting)
Methadone
Buprenorphine (Subutex, Suboxone)
Extended-Release Formulations
While individual experiences vary, here is a general timeline of what to expect during opioid withdrawal:
Attempting to withdrawal from opioids alone without medical supervision can be extremely difficult and potentially dangerous due to complications such as dehydration and the high risk of relapse.
Fortunately, there are effective treatment approaches that can significantly reduce the discomfort of withdrawal and increase the chances of successful recovery.
Treatment for opioid withdrawal typically involves a comprehensive approach that addresses both the physical symptoms of withdrawal and the psychological aspects of opioid dependence. The primary goal is to manage symptoms safely while transitioning the individual toward long-term recovery.
Medical detoxification, or detox, is often the first step in treating opioid withdrawal. This process involves clearing opioids from the body while providing medical supervision and support to manage withdrawal symptoms.
Opioid detox includes:
Medical detox typically lasts 5-10 days for most opioids, though this period may be extended for long-acting opioids like methadone. Throughout the detox process, vital signs are monitored, medications are administered as needed, and supportive care is provided to ensure safety and comfort.
Several medications have been approved for managing opioid withdrawal symptoms and supporting long-term recovery:
Medication-Assisted Treatment (MAT) combines medications with counseling and behavioral therapies to provide a “whole-patient” approach to treating opioid use disorders.
The FDA has approved several medications specifically for MAT:
Recovery from opioid use disorder is possible, and professional treatment can make the withdrawal process safer and more comfortable. Taking the first step is often the hardest part, but it’s also the most important.
At Peachtree Detox, our compassionate professionals are available 24/7 to answer your questions, verify your insurance coverage, and help you begin your recovery journey. The call is completely confidential and comes with no obligation.
The withdrawal process is temporary, but recovery can last a lifetime. With the right support, you can overcome opioid dependence and build a healthier, more fulfilling future.
Call us at 470-613-7881 and verify your insurance now.
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