Sublocade Shot (How It Works, Side Effects, + More)

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Sublocade is a type of Medication-Assisted Treatment and prescription medication used to treat opioid use disorder (OUD). 

For individuals struggling with opioid addiction, Sublocade can be a key component of a comprehensive treatment plan. At Peachtree Detox, we offer comprehensive detox programs in Atlanta that include the use of Sublocade, if clinically appropriate.

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What is Sublocade & How Does The Sublocade Shot Work?

Sublocade is a form of buprenorphine administered as a once-monthly shot. 

Buprenorphine is a partial opioid agonist, which means it binds to opioid receptors in the brain, reducing cravings and withdrawal symptoms without producing the same high as full opioids. Sublocade is injected subcutaneously (under the skin) and is slowly released over 30 days, providing continuous medication to help stabilize individuals in recovery.

This extended-release mechanism ensures that patients receive a consistent dose of buprenorphine throughout the month, reducing the need for daily medication.

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What Is The Sublocade Shot Used For?

Sublocade is primarily used to treat moderate to severe opioid use disorder and those undergoing opioid detox. It is often prescribed as part of a Medication-Assisted Treatment (MAT) program, which combines medications with counseling and behavioral therapies. MAT has been shown to improve recovery outcomes, reduce the risk of relapse, and help individuals achieve long-term sobriety.

Sublocade is usually prescribed to individuals who have already started treatment with buprenorphine and have stabilized on a daily dose of an oral version, such as Suboxone. Once stabilized, Sublocade helps maintain this balance by delivering a consistent dose each month.

Potential Side Effects of Sublocade

Sublocade is effective in treating opioid addiction. However, it can cause side effects, some of which may be serious. 

Common side effects include:

  • Nausea or vomiting
  • Headache
  • Fatigue or tiredness
  • Constipation
  • Insomnia or trouble sleeping
  • Sweating

In more rare cases, Sublocade can lead to more severe side effects, such as:

  • Injection site reactions (pain, itching, redness)
  • Liver issues (jaundice, dark urine)
  • Respiratory issues (trouble breathing)
  • Allergic reactions (hives, swelling)

If you experience any severe side effects or symptoms of an allergic reaction, it’s important to seek medical attention immediately.

Sublocade vs Vivitrol

Both Sublocade and Vivitrol are injectable medications used in treating opioid use disorder, but they function differently. 

Sublocade contains buprenorphine, a partial opioid agonist, while Vivitrol contains naltrexone, an opioid antagonist.

  • Sublocade: Helps reduce cravings and withdrawal symptoms by partially activating opioid receptors.
  • Vivitrol: Blocks opioid receptors entirely, preventing the effects of opioids if used.

Sublocade is generally more suited for individuals who are still experiencing cravings or withdrawal symptoms, whereas Vivitrol is often used after detoxification when a person has completely stopped using opioids.

Sublocade vs Suboxone

Suboxone and Sublocade both contain buprenorphine, but they differ in their administration and duration of action.

  • Suboxone: Comes in an oral form, typically taken daily, and contains both buprenorphine and naloxone to deter misuse.
  • Sublocade: Is a monthly injection of buprenorphine without naloxone, offering a long-lasting, consistent release of medication.

Sublocade can be more convenient for individuals who struggle with adhering to daily medication schedules or are at risk of misuse. Suboxone, on the other hand, offers more flexibility for those who prefer daily control over their medication intake.

How Long Does Sublocade Stay In Your System?

After the first injection, Sublocade stays in the body for approximately 30 days, gradually releasing buprenorphine into the bloodstream.

The effects of the shot are long-lasting, and the medication may remain detectable in your system for up to a month or longer, depending on factors like metabolism, dosage, and overall health.

What Is The Success Rate of Sublocade?

Sublocade has been shown to be highly effective in supporting long-term recovery from opioid addiction.

Clinical studies indicate that individuals treated with Sublocade experienced significantly reduced cravings and opioid use, with many achieving sustained sobriety.

As with any treatment, success rates improve when combined with comprehensive care, including counseling and other behavioral therapies.

How Long Do I Stay On Sublocade?

The length of time a person stays on Sublocade varies depending on individual needs and treatment progress. 

Many individuals remain on Sublocade for several months to a year or longer, depending on how they respond to treatment. 

Find Help for Opioid Addiction in Georgia

If you or a loved one is struggling with opioid addiction, Sublocade could be an effective part of your recovery journey. At Peachtree Detox, we offer comprehensive treatment plans, including Medication-Assisted Treatment with Sublocade, to help you achieve lasting sobriety. 

Call us now at 470-613-7881 learn more about how our detox programs in Georgia can support your recovery.

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